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Treatment of severe acute pancreatitis through retroperitoneal laparoscopic drainage

Chun Tang, Baolin Wang, Bing Xie, Hongming Liu, Ping Chen

Frontiers of Medicine 2011, Volume 5, Issue 3,   Pages 302-305 doi: 10.1007/s11684-011-0145-7

Abstract: A treatment method based on drainage via retroperitoneal laparoscopy was adopted for 15 severe acutepancreatitis (SAP) patients to investigate the feasibility of the method.SAP treatment via retroperitoneal laparoscopic drainage is an effective surgical method, resulting in

Keywords： severe acute pancreatitis (SAP)     laparoscope     retroperitoneal drainage     treatment    

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Total pancreatic necrosis after organophosphate intoxication

Rui Hou, Hongmin Zhang, Huan Chen, Yuankai Zhou, Yun Long, Dawei Liu

Frontiers of Medicine 2019, Volume 13, Issue 2,   Pages 285-288 doi: 10.1007/s11684-018-0626-z

Abstract: Cases of acute pancreatitis induced by organophosphate intoxication are encountered occasionally in clinics, but very few of them develop into severe pancreas necrosis and irreversible pancreatic function impairment

Keywords： organophosphate intoxication     severe acute pancreatitis     pancreas necrosis     percutaneous catheterization    

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A pilot study on Paxlovid therapy for hemodialysis patients with severe acute respiratory syndrome coronavirus

Frontiers of Medicine doi: 10.1007/s11684-023-1011-0

Abstract: and efficacy of nirmatrelvir/ritonavir (Paxlovid) therapy for hemodialysis-dependent patients with severeacute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

Keywords： Paxlovid     hemodialysis     SARS-CoV-2     viral load     chest CT scan    

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Clinical characteristics of 19 neonates born to mothers with COVID-19

Wei Liu, Jing Wang, Wenbin Li, Zhaoxian Zhou, Siying Liu, Zhihui Rong

Frontiers of Medicine 2020, Volume 14, Issue 2,   Pages 193-198 doi: 10.1007/s11684-020-0772-y

Abstract: The aim of this study was to investigate the clinical characteristics of neonates born to SARS-CoV-2 infected mothers and increase the current knowledge on the perinatal consequences of COVID-19. Nineteen neonates were admitted to Tongji Hospital from January 31 to February 29, 2020. Their mothers were clinically diagnosed or laboratory-confirmed with COVID-19. We prospectively collected and analyzed data of mothers and infants. There are 19 neonates included in the research. Among them, 10 mothers were confirmed COVID-19 by positive SARS-CoV-2 RT-PCR in throat swab, and 9 mothers were clinically diagnosed with COVID-19. Delivery occurred in an isolation room and neonates were immediately separated from the mothers and isolated for at least 14 days. No fetal distress was found. Gestational age of the neonates was 38.6±1.5 weeks, and average birth weight was 3293±425 g. SARS-CoV-2 RT-PCR in throat swab, urine, and feces of all neonates were negative. SARS-CoV-2 RT-PCR in breast milk and amniotic fluid was negative too. None of the neonates developed clinical, radiologic, hematologic, or biochemical evidence of COVID-19. No vertical transmission of SARS-CoV-2 and no perinatal complications in the third trimester were found in our study. The delivery should occur in isolation and neonates should be separated from the infected mothers and care givers.

Keywords： coronavirus disease 2019     severe acute respiratory syndrome-associated coronavirus     maternal-infant infection    

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Clinical manifestations and pathogen characteristics in children admitted for suspected COVID-19

Xiaofang Cai, Hanlan Jiang, Simin Zhang, Shengying Xia, Wenhui Du, Yaoling Ma, Tao Yu, Wenbin Li

Frontiers of Medicine 2020, Volume 14, Issue 6,   Pages 776-785 doi: 10.1007/s11684-020-0820-7

Abstract: Coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus

Keywords： coronavirus disease 2019     pediatrics     emergency     retrospective investigation     severe acute respiratory syndrome    

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Long non-coding RNA SAP30-2:1 is downregulated in congenital heart disease and regulates cell proliferation

Jing Ma, Shiyu Chen, Lili Hao, Wei Sheng, Weicheng Chen, Xiaojing Ma, Bowen Zhang, Duan Ma, Guoying Huang

Frontiers of Medicine 2021, Volume 15, Issue 1,   Pages 91-100 doi: 10.1007/s11684-020-0778-5

Abstract: bioinformatics analysis, and analysis of clinical tissue samples and observed that the novel lncRNA SAP30Knockdown of lncRNA SAP30-2:1 inhibited the proliferation of human embryonic kidney and AC16 cells andMoreover, lncRNA SAP30-2:1 was associated with HAND2 by RNA immunoprecipitation.Overall, these results suggest that lncRNA SAP30-2:1 may be involved in heart development through affecting

Keywords： congenital heart disease     Gene Expression Omnibus     lncRNA SAP30-2:1     cell proliferation     RNA immunoprecipitation    

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Experience gained in analyzing severe accidents for WWER RP using CC SOCRAT

Frontiers in Energy 2021, Volume 15, Issue 4,   Pages 872-886 doi: 10.1007/s11708-021-0796-2

Abstract: requirements regarding design basis accidents (DBAs) and beyond design basis accidents (BDBAs), including severeThe system of codes for realistic analysis of severe accidents (SOCRAT) (formerly, thermohydraulics (

Keywords： system of codes for realistic analysis of severe accidents (SOCRAT)     design basis accidents (DBAs)     severe    

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Outcomes of haploidentical bone marrow transplantation in patients with severe aplastic anemia-II thatprogressed from non-severe acquired aplastic anemia

Frontiers of Medicine 2021, Volume 15, Issue 5,   Pages 718-727 doi: 10.1007/s11684-020-0807-4

Abstract: Severe aplastic anemia II (SAA-II) progresses from non-severe aplastic anemia (NSAA).

Keywords： severe aplastic anemia     non-severe acquired aplastic anemia     haploidentical bone marrow transplantation    

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Development of an integrated modeling system for improved multi-objective reservoir operation

Lei WANG, Cho Thanda NYUNT, Toshio KOIKE, Oliver SAAVEDRA, Lan Chau NGUYEN, Tran van SAP,

Frontiers of Structural and Civil Engineering 2010, Volume 4, Issue 1,   Pages 47-55 doi: 10.1007/s11709-010-0001-x

Abstract: Reservoir is an efficient way for flood control and improving all sectors related to water resources in the integrated water resources management. Moreover, multi-objective reservoir plays a significant role in the development of a country’s economy especially in developing countries. All multi-objective reservoirs have conflicts and disputes in flood control and water use, which makes the operator a great challenge in the decision of reservoir operation. For improved multi-objective reservoir operation, an integrated modeling system has been developed by incorporating a global optimization system (SCE-UA) into a distributed biosphere hydrological model (WEB-DHM) coupled with the reservoir routing module. The new integrated modeling system has been tested in the Da River subbasin of the Red River and showed the capability of reproducing observed reservoir inflows and optimizing the multi-objective reservoir operation. First, the WEB-DHM was calibrated for the inflows to the Hoa Binh Reservoir in the Da River. Second, the WEB-DHM coupled with the reservoir routing module was tested by simulating the reservoir water level, when using the observed dam outflows as the reservoir release. Third, the new integrated modeling system was evaluated by optimizing the operation rule of the Hoa Binh Reservoir from 1 June to 28 July 2006, which covered the annual largest flood peak. By using the optimal rule for the reservoir operation, the annual largest flood peak at downstream control point (Ben Ngoc station) was successfully reduced (by about 2.4m for water level and 2500m·s for discharge); while after the simulation periods, the reservoir water level was increased by about 20m that could supply future water use.

Keywords： distributed biosphere hydrological model (WEB-DHM)     optimization     multi-objective reservoir     the Red River basin    

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with composition of lung microbiota and important taxa predicting clinical prognosis in patients with severe

Frontiers of Medicine 2022, Volume 16, Issue 3,   Pages 389-402 doi: 10.1007/s11684-021-0856-3

Abstract: Few studies have described the key features and prognostic roles of lung microbiota in patients with severestrongest independent association with lung microbiota (R2=0.033; P=0.018), followed by acute

Keywords： severe community-acquired pneumonia     lung microbiota     clinical improvements     7-category ordinal scale    

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Clinical manifestations and outcomes in severe ulcerative colitis

YANG Xuesong, YAO Wei, LIU Wenbin, LI Jun, LU Yumin

Frontiers of Medicine 2007, Volume 1, Issue 2,   Pages 192-195 doi: 10.1007/s11684-007-0036-0

Abstract: In order to evaluate the clinical manifestations and outcomes of severe ulcerative colitis (UC), we retrospectivelyreviewed 41 patients with severe UC from 144 consecutively hospitalized UC cases from 1988 to 2004.Of these severe cases, 92.7% (38/41) had pancolitis.Steroids played a main role in the remission of severe UC (61.0%).In conclusion, most of the severe UC patients respond well to drug therapy, but for individuals who are
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Structure Analysis, Forecasting and Urgent Measure for Surprised Severe Weather

OuYang Shoucheng,Xie Na,Hao Liping

Strategic Study of CAE 2005, Volume 7, Issue 9,   Pages 9-13

Abstract: and storm in Beijing and Shanghai and heavy rain gust in NE Sichuan are analyzed, and the surprised severe

Keywords： blown-ups     structure analysis     surprised severe weather     taking precautions against severe weather    

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Cross-sectional prevalence and pattern of non-anaemia severe malaria among 2–10 year olds in Sokoto in

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 969-974 doi: 10.1007/s11684-021-0912-z

Abstract: However, most reports on severe malaria in Nigeria are from hospital-based studies without accurate informationThis study aimed to describe the prevalence and pattern of severe malaria in a community in NorthwesternSevere malaria was diagnosed according to the World Health Organisation criteria.The mean age of children with severe malaria was 3.73 years, and the male–female ratio was 2:1.A relatively high prevalence of non-anaemia severe malaria was found in Wamakko.

Keywords： severe malaria     nigeria     malaria mortality     PfPR2-10     intermediate malaria transmission    

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Clinical study using mesenchymal stem cells for the treatment of patients with severe COVID-19

Lingling Tang, Yingan Jiang, Mengfei Zhu, Lijun Chen, Xiaoyang Zhou, Chenliang Zhou, Peng Ye, Xiaobei Chen, Baohong Wang, Zhenyu Xu, Qiang Zhang, Xiaowei Xu, Hainv Gao, Xiaojun Wu, Dong Li, Wanli Jiang, Jingjing Qu, Charlie Xiang, Lanjuan Li

Frontiers of Medicine 2020, Volume 14, Issue 5,   Pages 664-673 doi: 10.1007/s11684-020-0810-9

Abstract: The symptoms include fever, cough, dyspnea, early symptom of sputum, and acute respiratory distress syndromeMesenchymal stem cell (MSC) therapy is the immediate treatment used for patients with severe cases of

Keywords： coronavirus disease 2019 (COVID-19)     mesenchymal stem cell     acute respiratory distress syndrome     stem cell    

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Molecular pathogenesis of acute myeloid leukemia: A diverse disease with new perspectives

Felicitas THOL, Arnold GANSER

Frontiers of Medicine 2010, Volume 4, Issue 4,   Pages 356-362 doi: 10.1007/s11684-010-0220-5

Abstract: Acute myeloid leukemia (AML) is a very heterogeneous neoplasm of the hematopoietic stem cell.

Keywords： acute myeloid leukemia     mutations     risk stratification    

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Title Author Date Type Operation

Treatment of severe acute pancreatitis through retroperitoneal laparoscopic drainage

Chun Tang, Baolin Wang, Bing Xie, Hongming Liu, Ping Chen

Journal Article

Total pancreatic necrosis after organophosphate intoxication

Rui Hou, Hongmin Zhang, Huan Chen, Yuankai Zhou, Yun Long, Dawei Liu

Journal Article

A pilot study on Paxlovid therapy for hemodialysis patients with severe acute respiratory syndrome coronavirus

Journal Article

Clinical characteristics of 19 neonates born to mothers with COVID-19

Wei Liu, Jing Wang, Wenbin Li, Zhaoxian Zhou, Siying Liu, Zhihui Rong

Journal Article

Clinical manifestations and pathogen characteristics in children admitted for suspected COVID-19

Xiaofang Cai, Hanlan Jiang, Simin Zhang, Shengying Xia, Wenhui Du, Yaoling Ma, Tao Yu, Wenbin Li

Journal Article

Long non-coding RNA SAP30-2:1 is downregulated in congenital heart disease and regulates cell proliferation

Jing Ma, Shiyu Chen, Lili Hao, Wei Sheng, Weicheng Chen, Xiaojing Ma, Bowen Zhang, Duan Ma, Guoying Huang

Journal Article

Experience gained in analyzing severe accidents for WWER RP using CC SOCRAT

Journal Article

Outcomes of haploidentical bone marrow transplantation in patients with severe aplastic anemia-II thatprogressed from non-severe acquired aplastic anemia

Journal Article

Development of an integrated modeling system for improved multi-objective reservoir operation

Lei WANG, Cho Thanda NYUNT, Toshio KOIKE, Oliver SAAVEDRA, Lan Chau NGUYEN, Tran van SAP,

Journal Article

with composition of lung microbiota and important taxa predicting clinical prognosis in patients with severe

Journal Article

Clinical manifestations and outcomes in severe ulcerative colitis

YANG Xuesong, YAO Wei, LIU Wenbin, LI Jun, LU Yumin

Journal Article

Structure Analysis, Forecasting and Urgent Measure for Surprised Severe Weather

OuYang Shoucheng,Xie Na,Hao Liping

Journal Article

Cross-sectional prevalence and pattern of non-anaemia severe malaria among 2–10 year olds in Sokoto in

Journal Article

Clinical study using mesenchymal stem cells for the treatment of patients with severe COVID-19

Lingling Tang, Yingan Jiang, Mengfei Zhu, Lijun Chen, Xiaoyang Zhou, Chenliang Zhou, Peng Ye, Xiaobei Chen, Baohong Wang, Zhenyu Xu, Qiang Zhang, Xiaowei Xu, Hainv Gao, Xiaojun Wu, Dong Li, Wanli Jiang, Jingjing Qu, Charlie Xiang, Lanjuan Li

Journal Article

Molecular pathogenesis of acute myeloid leukemia: A diverse disease with new perspectives

Felicitas THOL, Arnold GANSER

Journal Article